High estradiol levels mtf. My mood and such is a lot better now but I wonder about breasts/nipples. There are two schools of thought on MtF hormone replacement therapy: 1: keep estrogen levels at the minimum effective dosage (this is because doctors believe estrogen (Provera) causes DVT blood clots, so they want to minimize the risk) and suppress T with the use of an anti-androgen (Spironolactone and Finestride being the most common in the US. My estradiol levels have been 1100-1500 pg/ml for the past year now, and I am feeling better, and healthier than I've ever been. This is confirmed by my latest blood levels. The WPATH Standards of Care 3 suggest monitoring once or twice a year after the first year of hormone therapy. So, I’ve been on HRT for about 6 months now, three month Lupron depot and 1mg (increased to 2mg as of two days ago, new prescription written before the blood work) Estradiol tablets that I take sublingually. I don't know how to really interpret these outside of them being inside or outside of the ranges given by my lab tbh. She told me to stop taking my estradiol. 5 mg Bica Testosterone 0. For example an estrogen level of 700 pg/ml is extremely high for HRT, yet 700 pmol/L is target range. Everything that I have read makes it seem like both these levels are in the wrong ranges, but my doctors said they have no plans in changing my doses. Super high E levels is bad, because anything over what your body can use will be converted into Testosterone. i have no clue what I should do. The goal of hormone therapy in trans women is to reduce the endogenous effects of testosterone such as coarse body hair and facial hair; and to induce female secondary sex characteristics such as breast and hip development. For transgender men, testosterone levels should be kept between 400-700 ng/dL. I always took my meds about 2 hours before the blood draw and they have never been high. So I’ve been on HRT for about 6 months now. 1–0. 5 years now. 20ml every week and I'm still at 350 p/ng on the 5th day after my injection. Turbulent_Security_7. I’ve been taking a 2mg tablet of estradiol sublingually 2x per day, 1mg of finasteride orally 1x per day, and 50mg of spironolactone Feb 13, 2024 · When estrogen is too high or too low you may get menstrual cycle changes, dry skin, hot flashes, trouble sleeping, night sweats, vaginal thinning and dryness, low sex drive, mood swings, weight gain, PMS, breast lumps, fatigue, depression and anxiety. Every time I get a blood test my estradiol levels are really high and my doctor reduces the dose. 5 mg of estradiol daily. 3 mL injection of 20 mg/mL EV weekly (and 50 mg spironolactone daily) and I just got my most recent lab results today on the patient Super high Estradiol levels 6 months in. New comments cannot be posted. Feeling over emotional. Here might be a number of resources concerning HRT Sep 9, 2021 · Baseline hormonal levels included an estradiol level of 26 pg/mL measured by liquid chromatography–mass spectroscopy (LC-MS), follicle-stimulating hormone (FSH) level of 5. To high estrogen is shown to correlate with multiple variations of cancer however, so this is a super unwise move regardless. For reference, I've been on HRT for about 2. Those hormone changes trigger physical changes that help better align the body with a person's gender identity. 25 mg/day. For some reason my estrogen levels will not make sense. Estrogen concentrations should be monitored and a new implant inserted when they fall below physiological levels. EV has a half-life of 5 days. Below my current doses and my levels in the screen. My current doses: - 2x Neofollin [1 ml] in week [first injection in Monday at 3:30 pm and second in Friday 7:30 am], Giving levels without the measuring standard is of little value, in the future please include pg/ml, pmol/L etc. 02, respectively, by Wilcoxon matched pairs test). ’s (2004) finding that transdermal estradiol produced “serum estradiol/estrone ratio closer to premenopausal values” in postmenopausal women, compared to those taking oral estradiol, as well as Bagot et al. In a 1989 retrospective study, combined treatment with estrogen and cyproterone acetate [an androgen-blocker] was associated with increased depressive mood changes (Asscheman, Gooren, & Eklund). Methods: This prospective study included 82 transgender persons who completed 1 year of treatment, 45 male-to-female individuals (MtF’s) (mean age± S. With Estrogen, I need a minuscule amount to get my levels super high. If you're on 4mg of E, discuss with your doctor to lower the dosage to 2mg of E. For the record, I'm 4 months into HRT, transfemme, my dosage is 3 pumps of estrogel each night at 11 pm, so 1. excessively high levels of estrogen can cause an increase in the amount of prolactin produced and lead to hyperprolactinemia, which has a litany of nasty symptoms. T: 400ng/dl. However, my tests in June 2023 gave me 2888 pmol/L of estradiol, which is within the pregnant range. I’m down to . Equivalent-Wafer-222. The "rule of thumb" advocated by most medical professionals is to shoot for roughly the levels cis women have during the luteal phase, which tend to be in the 100-200pg/mL range. I've just done my first control labs a couple of days ago, results were: testosterone: 18. 54. Today I got tests again and they gave me 4363 pmol/L. (Now, for other body systems, having too much of a e. When estrogen levels are high, sperm levels may fall We would like to show you a description here but the site won’t allow us. The Endocrine Society Clinical Practice Guideline (2017) recommends 100 to 200 pg/mL – which translates as 367. 25 mg injection every 3 months. Jan 30, 2015 · Symptoms of high estrogen in people assigned male at birth can include: Infertility: Estrogen is partly responsible for creating healthy sperm. 1. 5 mL (Weekly), Progesterone 200 mcg Capsule (Once a day), and Spironolactone 100 mg Tablet (Twice a day) Locked post. Here are references in case. Results: 371 MTF patients were identified, 41 received an estradiol transdermal patch. Second… 73 pg/ml isn’t high, it’s actually reasonably low. That should give you higher estradiol levels and lower estrone levels. That means your levels will have a steady decline from the injection time until the 5th day and dramatically drop regardless of the amount you inject. My estrogen levels were at 67 pg/mL, which is too low, and I convinced her to switch me to oral but wouldn't increase the dosage. For some context, I’m on 10mg/0. feeling dizzy, lightheaded, or Hi, my Estradiol range is currently 48. 09 pmol/L to 734. 5-9. I was surprised to find that my endo didn’t want my baseline levels before HRT but it was Feb 12, 2021 · The National Guidelines for Gender Affirming Healthcare (2019) recommends a pmol/L level of up to 500, but also emphasise that dosage decisions should be led by the patient. Assuming you're US, you'll be on pg/dl, and if that's an accurate read, your estrogen levels are twenty times the bottom of the target range. 0 IU/L, luteinizing hormone (LH) level of 3. Feb 1, 2019 · Generally, 100 mg is inserted for most transwomen, but a supplementary 50 mg implant can be added for patients with a high body mass index. Adjust the dose as needed (packets available as estradiol 0. 25 mg topically once a day to the skin of either the right or left upper thigh. Exposure to those levels isn’t going to do much unless it’s over years. Feminizing Hormone Therapy. I’m waiting to hear back from my doctor but I also wanted to see if anyone had any advice. As always, talk to your doctor, and don't only listen to internet randos. 3ml weekly): 332 pg/ml E, 14 ng/dL (after this check, I stopped my T blocker) . Estradiol levels seem a little high Advice Question Hey all, just got my levels back from my last visit to planned parenthood and my estradiol levels were at 573pg-ml, and when I asked my doc about it seeming high he was saying it is fine and not to worry. Having said that, I felt the best when my estradiol levels were screaming high and my testosterone was still above ideal "female" levels. Estrogen level issues again. Intense desire to cuddle. Regular blood tests are essential for trans people who are self-medicating for two main reasons: To make sure you’re on the right hormone dose. Mine dropped to 40 when I started hrt and hasn't shifted either way since then. 9mUI/mL. My levels are currently at 492pg/ml Estradiol and 4ng/dl Testosterone. 02 mg oral ethinyl estradiol daily, 2 mg of oral 17β-estradiol daily (or 0. infection. For a summed up history: My endocrinologist kept me at 1. Symptoms are headache, bloating, water retention, weight gain, anxiety, depression, brain Many endos strive for levels of e of at least 120-150 pg/ml, or above, and for levels of t below 85 ng/dl. Testosterone level is very average at 683, but I am just baffled at the E. ago. Transdermal Metered-Dose Pump. We've adjusted dosing over the last 2 months and my levels are back down to the 200s, T is in cis-female range (50s ng/dl I think). • 7 yr. However the guidance I can find from healthcare providers has this as just below normal range, so they'd consider me slightly under. I take sublingual tablets, and have been bouncing around on the dosages. My levels at last check were 297 after 7 days so for you to have 211 at 9 days doesn't seem that weird to me. Ideally, you should include carbohydrates in your MTF diet or FTM diet to help increase your energy levels, but try to choose healthier unrefined versions: e. Standard are 10-20 mg per week. I have been getting signs of testosterone levels increasing again, such as increased acne, increased sex drive and return of ejaculation. it won't suppress your T just block it from binding. Ten of the girls had 17B-estradiol levels below the detection limit, mostly around midnight, at 2200 and 0200 h. Some people subscribe to the school of thought that if it allows you to suppress T without an AA, that’s a good trade off. Cis women can sport estrogen readings in the thousands when pregnant, and there are natural spikes in their hormonal cycles. Two subjects (both transgender women) were excluded due to having a BMI >50 kg/m 2; 24 transgender women were excluded due to the use of Up to 2023 this regimen gave me pretty good levels, a bit in the high range but completely fine. Also, high E1 levels (which happen with pills) are somewhat dangerous, but you're avoiding that with injections. Instead of swallowing the pills, I suggest switching to taking them sublingual every 8 hours. 75, 1, and 1. Removing testicles does not remove your body's hormone regulation mechanism. Estradiol valerate in oil injection . The first set of figures are in units commonly used in the US, while the second set are in standard international units. 4 nmol/L (it got nuked lmao L bozo) Estradiol 414 pmol/L My latest blood test results: E2: 81pg/ml. Reply. 4 to 4. According to the doctor those are cis female levels during ovulation but they are still a bit high… Mar 4, 2021 · Intramuscular injections resulted in higher levels of estradiol than oral and transdermal routes for transgender women, whereas all hormone therapy routes result in similar testosterone levels in Hi everybody. However, breast development is often modest, 5–8 and many individuals seek surgical breast augmentation. Of these 41 patients, 16 of them were placed on a transdermal patch due to failure to achieve target 17-β-estradiol levels on maximal oral therapy. L. ;) Different countries or even different labs within a country can use different standards. If you're taking high amounts of estrogen sublingually then your estrogen levels will spike dramatically, which means they will fall more dramatically too. Pregnant women have far higher levels than that, so it’s not like the health impacts are completely unknown. My endo was surprised about it, and so am I, to be honest. 8 ng/dl (614 pre-HRT), estradiol: 1321 pg/ml (24. So I recently went in for my check up for my estradiol levels (8 months HRT) and the lab results came back at 975 pg/mL. 19 pmol/L. 6 pmol/L) Female (premenopausal): 30 to 400 pg/mL (110 to 1468. Sort by: Search Comments. Once I was on 8 mg and over 100, my feminization sped up. I have no idea what could’ve caused this and my endocrinologist and doctor don’t either. Jul 31, 2019 · Mijares additionally cites Girdler et al. High estradiol levels. However, only 84 transgender women and 71 transgender men met the inclusion criteria. 0). You will likely be told to reduce your dose or switch injecting every 2 weeks. Primarily it's the hormone being zero and the consequences of this. Is it worth checking if i’m maybe intersex or have any other condition that might affect estrogen levels? These are my levels now after 1 month and a half on 4 mg Estradiol and 12. Estradiol: 65pg/mL. Like 1563 pg/mL. Call the endo's office when they open and leave a message noting that you're concerned. You're hormones being too high or too low on either side can cause lipid and triglyceride problems and can damage the heart or cause heart attacks. I'm eating weird shit and fart constantly. Breast development is a key clinical outcome for many transgender individuals. wholegrain rice, pasta, wholemeal bread, cereals and starchy veg (potatoes, carrots, parsnips). [deleted] • 2 yr. Most of the worry about estradiol being too high is way overblown unless you already have prior risks such as obesity, diabetes, or genetic conditions that put you at elevated risk. 52 mg) topically to upper arm once a day; dose Test came back with Testosterone at a nice 11 nmol/L, which they were happy with. 5ml Val (per week) and 100mg Spiro (per day). If you have… On 8 mg I’m in the 130’s. Some titrate up slowly, etc. Spironolactone usage was high at >90% over the first 2 years of the study. From what the sheet says estrogen is a bit higher than normal (10-40 pg/mL is the range) and FSH is a bit lower than normal (1. Especially changes to my face. A table of hormone levels of interest to transgender people. My total estrogen level is at 225 pg/mL, which seems to be much higher than what an AMAB person should be at. But That is very high for a mid cycle reading. 7 to 183. Low levels of estrogen was unable to maintain testosterone suppression. If pregnant women can tolerate levels over 2000 for nine months straight with few adverse effects (related to the estrogen levels anyways), I'm sure you'll be fine at a few months around 1000. Between 3 and 6 months for reaching the target levels may be reasonable. I went to another endocrinologist who gave me 4mg/day oral. Knowing how your hormone levels compare with standard reference ranges will ensure you receive the correct dose. That's more than a bit out or range. • 2 yr. Sep 26, 2018 · An estradiol test is a simple blood test, and its risks are low. Drakolyik. Iirc the expected female range is 0. Triptoreline 11. It can also affect your pituitary gland. This includes a full blood count, renal and liver function, blood pressure and lipids, and blood glucose for patients with risk factors. An in vitro study found that a high excess of estrone interferes with the positive cooperative binding of estradiol and its receptor, by inducing a change in the estradiol-receptor complex that favors the nonactive The results may vary, depending on the person's sex and age. Mar 15, 2024 · Initial dose: Apply 0. Both hormones at the appropriate level is healthy for the heart. Estradiol is a lot more potent than Estrone. 34±13 years) and 37 female-to-male The thing is with Estradiol Valerate, you shouldn't even be doing weekly injections. And how fast those ranges are reached can be individual. Physiologically, this requires a suppression of endogenous androgens and the addition of estrogen. Prog: 0. The second most common estrogen regimen was intramuscular estradiol valerate or cypionate with rates steadily increasing over time. I have been taking 3 mg per week through intramuscular injection. The timing of measurements depends on the type of therapy used. 1mg/day(!). After a couple of hours you'll be close to baseline. 257K subscribers in the MtF community. It's me again, I'm sorry. 4 pmol/L) Female (postmenopausal): 0 to 30 pg/mL (0 to 110 pmol/L) Normal value ranges may vary slightly among different laboratories. Add a Comment. Not the drug blocking the hormone. We investigated the effectiveness of oral estradiol While testosterone can convert to estradiol, the reverse actually doesn't happen. If you feel fine, and you are feminizing, your estradiol levels are fine. Estradiol should be kept between 100-200 pg/mL. 5ml weekly injections, trough reading): 604 pg/ml E, 13 ng/dL T February 2023 (0. The longer-term effect was a slow decline in my level of depression, starting after about 2 months and completing after about a year. I'm super confused how one of them can I'm going to say Its a bad test, I'm on 200 spiro and was on 6mg estradiol and my test came back at 155 estrogen and my t was a 3. Adjust and monitor. FSH: 0. 05 mg transdermal estradiol patch twice weekly), while a typical dose for transgender women is 5–20 mg intramuscular estradiol valerate (or 0. My dosage was lowered from 0. ’s (2010) study suggesting that the greater estrone levels caused by oral estradiol use may Tell your doctor not to worry and that any danger of high Estrogen levels is overstated and likely was taken from the study that included the now known "bad drugs" premarin and medroxyprogesterone. 025 to 0. Oct 15, 2019 · Estradiol is an important sex hormone and an important feedback regulator of the hypothalamo-pituitary axis and the serum levels of testosterone (T), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). Jul 5, 2018 · That estradiol treatment enhanced within network connectivity among those women with high levels of childhood adversity, but had no appreciable impact on those with low levels of childhood adversity, suggests a differential impact of gonadal steroids on brain structure and function based upon adverse exposures during critical windows of May 14, 2024 · Feminizing hormone therapy is used to change the body's hormone levels. I'm not sure that the body would product high levels of estrogen during the middle of every menstrual cycle and during pregnancy if receptor burnout at the 1500 pmol/L level was an issue. 25, 0. Got my bloodwork done about 3 days after my first estradiol valerate injection (was on estradiol tablets before this). So far I have been getting very good results with basically no side effects. After researching it, I found that because it's delivered transdermally, it's equivalent to swallowing a 2mg estradiol pill. • 1 yr. If estrone gets too high, it can increase the possibility of blood clots and mood swings. 5ng/mL. There is at least a small increase in the risk of blood clotting. Getting an orchi is like removing the transmission in a car but leaving the On one hand I'm super happy to have already reached cis levels so early in my tgherapy, but on the other I'm a bit confused and concerned as my estradiol levels appear extremely high, analogue to cis women at 3 months into pregnancy, and very different as reported by other trans women who are settled between 200 - 300 pg/ml. 5ml of 20mg/ml so I’m injecting 10mg Levels taken 3. These are pretty high for not being on HRT so i’m pretty surprised by these. 8 mg is the max dose. I'm depressed and lazy. I’m passing at this point. Hi! I should note though that this was my old dose, it turned out to be too high and I was eventually moved down to 0. Source: Massachusetts General Hospital, New England Journal of Medicine. Have a fun weekend and chat with your doc about it next week. It is recommended that levels are monitored at baseline, every 3-4 months for the first year, and then annually once your patient’s estradiol and testosterone levels are adequate and stable. FaceCweam. We thought it was maybe a fluke. Hi All, I just had my second blood work done and I got high results for my estradiol levels. LH: 8. Apr 1, 2019 · A total of 319 subjects were seen for gender-affirming hormone therapy between September 1, 2008 and August 22, 2016. When I switched to injectable monotherapy my Estradiol levels got way high over 6 months (1000pg/ml at trough). My Oestradiol level however was 332 pmol/L, which they were classing as super super high. The E basically hangs around until such a time as it gets unblocked. Btw, when my endo put me on patches, I was worried about the dose - 0. The statistical analysis indicated a diurnal rhythm, with 17B-estradiol levels at 1000 h significantly higher than those at 2200 and 0200 h (P < 0. So there is such a thing as bad estrogen or estrogen buildup, this occurs when you stop absorbing estrogen from your receptors so. I’ve been on Val for at least two months at Aim: The aim of this study is to get more insight into the effect and time-course of changes in serum prolactin levels during cross-sex hormone therapy. 2. g. And even then, it probably wouldn’t be bad. May 3, 2021 · Target serum level for estradiol >100 pg/mL is recommended (but may be lower in certain clinical circumstances). You were on a very low dose for a long time a 2mg jump shouldn't make your levels that high. Prolonged levels like that can drastically increase DVT/blood clots. However, any test involving a needle carries some risks, such as: bleeding. Jun 2, 2022 · After this, if there aren’t any issues with levels being too high or too low, they can decrease lab monitoring to once or twice a year . I take it every four hours when possible so that I can keep a more consistent level throughout the day. My levels are currently 340ish E, single digit T and progesterone has been added. August 2022 hormone levels (reflecting levels from sublingual tablets): 59 pg/ml E, 77 ng/dL T November 2022 (0. 3 mg/ml as requested, but not completely cut off. The duration of drug delivery with implants is on average 6–12 months. Nov 5, 2017 · Standard Male and Female Hormone Level Ranges. In the paper "Transdermal Estradiol Therapy For Advanced Prostate Cancer—Forward To The Past?” J. As long as you’re between 100-200 you’re fine. I don’t know what happened I mean like once a week some times I will forget to take them (4mg in the morning and 2mg at night sublingually with 100mg spironolactone) usually the morning dose. Want to ask my doctor if I can get my levels First off, you’ll be fine. It may take some time to get the dosage right. Plus I'm feminizing at a steady rate. Oct 11, 2021 · Our results are in contrast with other studies suggesting that high estrone levels can act as an estrogen antagonist (14, 35-37). Initial dose (Elestrin): Apply 1 pump (0. Apr 19, 2021 · For trans feminine patients, 92% were initially started on oral 17β-estradiol and the mean dose generally increased over time. 25ml of 20mg/ml (every 6 days). I believe SHBG is only raised through oral estradiol, not injections or transdermal. bruising. Estrogen is a naturally occurring hormone that your body produces to aid in sexual development Very high levels for too long can also increase risks of developing various estrogen-related cancers (breast cancer primarily). Way too high. In a menstrual cycle estrogen normally hits it's highest around 400 briefly right before ovulation. Transgender women should try to keep their testosterone less than 50 ng/dL. Overview. 001 and P < 0. 5 mg/ml to 0. 6,9 Two studies have reported the influence of serum estradiol concentration on breast development in transgender individuals. 7 pg/mL and my T is at 378. 4 pre HRT) And the research showing that high estradiol levels are bad was done on synthetic estradiol. 711 is definitely too high. Makes me think, I just opened a new bottle, maybe I was given 40mg/ml instead of 20mg/ml, will have to check when I get home. hormone for a short time can downregulate receptors and then there's problems when the levels are The UCSF Transgender Care and Treatment Guidelines 2 suggest that annual monitoring is reasonable after reaching the desired range. (high-dose oral contraceptives/birth control pills) Body fat: Fat tissue ( adipose tissue) secretes estrogen. I'm drinking heavily and smoking 3 packs a day. A subreddit devoted to transgender issues pertaining to male-to-female or trans feminine people. try bicalutamide. They look good, but my provider suggested lowering my dose as my estrogen is “on the higher end” and they want to avoid side effects of that. I use . Switched from pills to injections and the next time my blood was drawn, E levels were over 700 pg/ml. Orchi doesn't really change your body's needs for a baseline of sex hormones, it only removes your body's primary way of making sex hormones. 5, nmol/l so anywhere in that range i assume is good. Typical levels for women are between 15 and 70ng/dL. 5 Share. Oct 12, 2023 · Transgender women with testis intact may require relatively high doses of estrogens to suppress testosterone into the female range, even with the addition of a GnRH agonist or an antiandrogen agent. I've double up before and that and kinda light headed is all i felt and that. (N Engl J Med 2004;351:1548-63). In May, I got a call from my doctor; my estradiol levels from May 4th were too high. 4 mg transdermal estradiol patch twice weekly). Sep 21, 2020 · Once insulin and cortisol rise too high, they work to decrease testosterone. On Google, I read that having too high estrogen and too low progesterone (I have none since I don't take it as a mtf trans woman) can cause estrogen dominance, which would explain these awful symptoms I've been having since I increased my estradiol dose. Pregnant women can have their E2 go as high as 2500pg/mL in the first trimester, and up to 7100pg/mL in the second, and up to 6400pg/mL in the third. 25 mg) Maximum dose: 1. I want the estrogen levels to show at their lowest (without cheating/lying) so I can make a case for more (because "bring on the boobs!" 😉). Ockrim, Estradiol patches were used by themselves to maintain Estradiol levels of 1000 pmol/l (272 pg/ml) which resulted in “castration levels” of LH and T within three weeks in men with prostate cancer. D . i've had no issues with it at all and have been on it for >3 years. In some cases, people seeking feminizing hormone therapy experience discomfort or distress because their gender identity differs from their sex assigned at birth May 1, 2018 · Purpose: Maintaining cross-sex hormone levels in the normal physiologic range for the desired gender is the cornerstone of transgender hormonal therapy, but there are limited data on how to achieve this. If your hormone levels are lower than they should be, that could mean you’re not LH and FSH are high because your dose is "too low". 5 IU/L, and total testosterone level of 701 ng/dL (by LC-MS), all within reference range for an individual recorded male at birth. The immediate, lasting mental effect for me was that my mental narrative got quieter, and I gained the ability to pause it. Depression has been tied to both high and low testosterone levels in women (Rohr 2002) and transsexuals’ isolation (Rauchfleisch 1998). If you are consistently lower than that it can cause issues with breast tissue development and some other health issues, iirc. 1mUI/mL. 5mg subdermal for over a year. I found my groove after a few years on hormones. Cholesterol The way you can check for this is with blood tests. Too high according to my doctor. Male: 10 to 50 pg/mL (36. Opinions vary on this. Estradiol biosynthesis is initiated by the synthesis of the 19-carbon steroid hormone pregnenolone from cholesterol. Cis women's estradiol levels vary widely throughout their cycle, from as low as 30-50pg/mL (during the folicular phase), to as high as 300-400 (during ovulation). 5, 0. My body is very masculine and I have lots of body hair, so I never would have guessed I have high estrogen. I got a blood test back that said my estrogen levels were 383 pg/ml and planned parenthood says that this is too high and that I should lower my dose to 2 mg per week. High estradiol levels mtf injections So I got bloodwork done 4 days after my last injection (I do 0,18mL Estradiol Valerate every 5 days) and my levels were 1969 pmol\L. My last blood test (in may, and a day past the middle of my injection cycle) said my T levels were 7 ng/dl (below normal range for cis women) and my e levels were 429 pg/ml (which is normal). 20 ng/dl is fine from what I understand. Typical estradiol regimens include ( table 3 ): Transdermally, 0. My body holds on to Estrogen for a LONG time for some reason. Jun 2, 2021 · Breast development. He wants to get me down to about 200 of/ml estradiol. Results say my estradiol levels are 1604 pg/ml, way way too high. Feb 9, 2022 · A variety of factors can contribute to high estrogen, including: Medications: Hormone therapy to boost low estrogen levels may cause your levels to become too high at first. It'll take time to adjust your regimen and get you to where you need to be. 75 days after injection: Estradiol: 719 pg/mL Higher than I was expecting honestly. 2 mg/24 hours. Medications that I’m taking for HRT are: Estradiol Valerate IM 40mg/0. For example, a typical dose for hormone replacement therapy is 0. df zw dk bu wq ag vd hy sj oo